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SYMMETREL (AMANTADINE HCL) TABLETS AND SYRUP: PRESCRIBING INFORMATION
Symmetrel (Amantadine Hydrochloride) is designated generically as amantadine hydrochloride and chemically as 1-adamantanamine hydrochloride.
Amantadine Hydrochloride is a stable white or nearly white crystalline powder, freely soluble in water and soluble in alcohol and in chloroform.
Amantadine Hydrochloride has pharmacological actions as both an anti-Parkinson and an antiviral drug.
Symmetrel is available in tablets and syrup.
Each tablet intended for oral administration contains 100 mg amantadine hydrochloride and has the following inactive ingredients: magnesium stearate, hydroxypropyl methylcellulose, microcrystalline cellulose, sodium starch glycolate, FD&C Yellow No. 6.
Symmetrel syrup contains 50 mg of amantadine hydrochloride per 5 mL and has the following inactive ingredients: citric acid, artificial raspberry flavor, propylparaben, methylparaben, and sorbitol solution.
INDICATIONS AND USAGE
Symmetrel indications and usage
Amantadine Hydrochloride (Symmetrel) tablets and syrup are contraindicated in patients with known hypersensitivity to amantadine hydrochloride or to any of the other ingredients in Symmetrel.
Symmetrel drug interactions
Symmetrel nonclinical toxicology
USE IN SPECIAL POPULATIONS
Symmetrel use in special populations
Symmetrel adverse reactions
DOSAGE AND ADMINISTRATION
Symmetrel dosage and administration
Symmetrel (Amantadine Hydrochloride, USP) is available in light orange, convex curved, triangular shaped 100 mg tablets with "SYMMETREL" debossed on one side and plain on the other side as bottles of 100.
As a clear, colorless syrup [each 5 mL (1 teaspoonful) contains 50 mg amantadine hydrochloride] in: 16 oz. (480 mL) bottles.
Store at 25°C (77°F), excursions permitted to 15°-30°C (59°-86°F). [See USP Controlled Room Temperature].
Dispense in a tight container as defined in the USP, with a child-resistant closure (as required).
Manufactured and distributed by Novartis, Endo Pharmaceuticals companies and their divisions.
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